Posted on : Friday 18 October 2019

Job title : 2019/10/18 – Research Engineer Position (2 years)

Organization : The Institut de Chimie Moléculaire de l’Université de Bourgogne (ICMUB), in Dijon is involved in the development of innovating tools for medical imaging techniques such as nuclear imaging (PET/SPECT) or fluorescence imaging. The group is specialized in the design of new imaging probes, such as chelators (i.e. DOTA-like compounds), fluorophores, as well as their immobilization on biological vectors (peptides, antibodies, ...) through innovative bioconjugation chemistry.

Mission : In the frame of the MULTIMOD program supported by the Regional Council and the European Union, ICMUB is seeking a highly motivated candidate with strong chemistry and bioconjugation background to design, prepare and characterize protein or peptide-based conjugates for imaging/therapy purposes. The selected candidate will have the opportunity to closely interact with the local imaging cluster and the preclinical imaging platform members. He/she will contribute to the team’s mission of delivering in time, fully defined conjugates to our academic/industrial partners.

The successful candidate will have the following responsibilities:
- Involvement in various R&D and public/private programs
- Synthesis of bioconjugates, by modification of home-made proteins/peptides or coming from our partners
- Development and implementation of robust analytical methods to fully characterize antibody-based conjugates
- Synthesis of specific molecular probes, in collaboration with researchers involved in technology transfer programs
- Preparation of technical documents, summary reports and regular updates on project status
- Participation to valorization actions.

Starting date: Asap

Locality : Dijon, France

Remuneration :

Degrees required : PhD degree

Skills required : Proven track record in organic chemistry and protein labelling - Strong experience with chromatography and mass spectrometry data analysis and method development - Ability to execute technical tasks independently to achieve projects goals on an established timeline and to work in a collaborative environment - Highly organized and able to manage multiple tasks - Excellent written and oral communication skills, adaptability. Preferred but not required: - Experience in radiochemistry and molecular imaging

Contact : Prof Franck Denat, franck.denat@u-bourgogne.fr