Coordinator : Pr. Daniel Fagret

Project manager : Under progress

Local administrative coordination

Université Grenoble Alpes

 

 

The “in vivo Imaging in Grenoble” platform is dedicated to research in preclinical and clinical imaging. It brings together more than 120 permanent researchers, 77 doctoral and postdoctoral researchers, chemists, physicists, engineers, technologists, biologists, pharmacists and doctors. Its aim is to develop the most relevant equipment and methodologies for the in vivo exploration of pathophysiological processes in animal models and in humans. The performance of these systems exceeds those of commercial systems. The equipment and associated expertise are open for collaborations to the academic and industrial scientific community.

 

Main expertise

The methodological research focuses on (i) new optical equipment and X-ray imaging and nuclear detectors, (ii) new imaging agents for the clinical studies using optical imaging and nuclear medicine, (iii) methodological developments in intravital microscopy and in neurophysiology and (iv) perfusion imaging using MRI. The combination of this scientific, technological and applied expertise allows for greater scale coherence in integrated multimodal imaging for new in vivo molecular imaging solutions.

Imaging modalities and expertise available include the following ones:

• Small animal nuclear imaging systems (PET-CT , SPECT-CT, and 3T MR-PET) with research in radiochemistry (Tc 99m, I 123, In 111, F18, Ga68, Cu64,Y90, Lu177, Ac 225),

• Small animal Ultra-High Fields MRI scanners (4.7 T, 7T and 9.4 T),

• Fluorescence, bioluminescence and opto-acoustic imaging systems

• Human 3T MRI scanner,

• Clinical PET CT scanner,

• MEG and EEG,

• Devices for the study of neurophysiology.

Imaging platforms and contact

• Multimodal interventional imaging (per op MRI, SPECT, MEG, confocal microendoscopy, fluorescence microscopy, intravital microscopie) : Clinatec [http://www.clinatec.fr/clinatec/]

• Optical and opto-acoustic imaging : Optimal – Jean-Luc Coll, jean-luc.coll[at]univ.grenoble-alpes.fr; Véronique Josserand, veronique.josserand[at]univ.grenoble-alpes.fr [https://iab.univ-grenoble-alpes.fr/Plateformes/imagerie-optique-petit-animal-optimal]

• Nuclear and US imaging: GAIA – Catherine Ghezzi, Catherine.Ghezzi[at]inserm.fr; Alexis Broisat, Alexis.Broisat[at]inserm.fr – [https://lrb.univ-grenoble-alpes.fr/plateforme-gaia]

• MRI : IRMaGe – Emmanuel Barbier, Alexandre Krainik, AKrainik[at]chu-grenoble.fr https://neurosciences.univ-grenoble-alpes.fr/fr/recherche/plateformes-technologiques/plateforme-irmage/

• Neurophysiology, EEG, TMS : Neurophysiology – Olivier David, https://neurosciences.univ-grenoble-alpes.fr/fr/recherche/equipes-de-recherche/stimulation-cerebrale-et-neurosciences-des-systemes-olivier-david-/

Laboratoires de recherche associés :

U1039 , lrb.univ.grenoble-alpes.fr ;U1209, iab.univ.grenoble-alpes.fr ; U1216 (team 5),neurosciences.univ.grenoble-alpes.fr ; U1205, CLINATEC, clinatec.fr; UMR 5250