Coordinator : Hervé Saint-Jalmes, herve.saint-jalmes@univ-rennes1.fr

Project manager : under progress

Local administrative coordination : Université de Rennes 1 et Université de Nantes

 

Presentation

FLI’s Grand Ouest node is one of three nodes integrated into the infrastructure on June 1, 2020.

The node includes three imaging platforms,

• NeurInfo (imaging and neuro-informatics platform),
• PRISM (Multi-modal Imaging and Spectroscopy Research Platform),
• CRCINA (Research Center in Cancerology and Immunology Nantes-Angers), located in Rennes, Angers and Nantes.

Affiliated to the Biogenouest network, these platforms are under the main supervision of the University of Rennes 1, University of Nantes, University of Angers and INRAE.

The equipment for in vivo imaging spans all modalities with the exception of optical imaging. This state of the art equipment is associated with a specific expertise of each platform.

 

For preclinical research, the node offers an access to the following equipment:

• A 7T MRI (located in Angers), a 4.7T MRI (located in Rennes) dedicated to small animal imaging and spectroscopy, and a 1.5T MRI (located in Rennes) dedicated to large animal imaging as well as high resolution NMR systems on the PRISM platform (https://www.pf-prism.org/les-equipements/ ),
• Nuclear imaging devices for large animal model including 1 PET-CT, 1 CT scanner, and 2 gamma cameras on the PRISM platform (https://www.pf-prism.org/les-equipements/ and for rodents including PET-MRI, a PET-CT and a unique 3-photon PET device at CRCINA in Nantes (http://www.crcina.org/recherche/departement-3-nohmad/equipe-13-nuclear-oncology/ ). The platforms operate also radiopharmacies for the synthesis and quality control of radiolabeled molecules.

 

Clinical research is mainly based on MRI and computing modeling implemented on the NeurInfo platform (https://www.neurinfo.org/ ). Neurinfo platform is equipped with a 3T MRI installed at the Rennes University Hospital.

 

Main expertise

 Associated with the equipment, the Grand Ouest node has expertise in the following areas:

– Quantification of physiological and metabolic parameters (perfusion, concentration of bioactive molecules, body composition, receptor density) and other biomarkers (water diffusion, relaxation times, etc.) for preclinical applications in oncology and nutrition (PRISM platform),

– Molecular imaging applied to immunology and oncology,

– Neuro-informatics in the context of diseases of the nervous system,

– Population imaging.

 

Imaging platforms and contact

 PRISM (https://www.pf-prism.org/les-equipements/) / François Mariette, mariette[at]inrae.fr   

• CRCINA à Nantes (http://www.crcina.org/recherche/departement-3-nohmad/equipe-13-nuclear-oncology) / Michel Cherel, michel.cherel[at]inserm.fr
• NeurInfo (https://www.neurinfo.org/) / Christian Barillot, barillot[at]irisa.fr

Research laboratories associated to the platforms

 UMR 1232 INSERM- CNRS ERL 6001 CRCINA (http://www.crcina.org/recherche/departement-3-nohmad/equipe-13-nuclear-oncology/)

• Aniscan, US 1395, INRAE
• UMR CNRS 6074, ERL U1228 Empenn (https://team.inria.fr/empenn)
• UMR INSERM 1099, LTSI, METRIQ team (https://www.ltsi.univ-rennes1.fr/METRIQ_home)
• UMR INSERM 1066 – CNRS 6021, MINT (http://mint.univ-angers.fr)